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Penn State: Bridging Microbiome Science and Antimicrobial Resistance: A One Health Perspective

By Nicole Reynolds posted 03-26-2024 04:37 PM

  

Dr. Nichole Ginnan, the Research Project Manager at the One Health Microbiome Center at Penn State, brings a wealth of experience in agricultural microbiomes and sustainable agriculture. With a focus on developing alternatives to antimicrobial use, Dr. Ginnan's expertise lies in microbial biological controls. In her discussion of antimicrobial resistance (AMR) from a microbiome science perspective, she highlights the center's unique approach.

The One Health Microbiome Center, under Dr. Seth Bordenstein's leadership, stands out as the first microbiome center to formally integrate a One Health approach. This integration brings together experts from diverse fields, including human health, environmental health, and agricultural health, ensuring a comprehensive understanding of microbiomes' role in global health systems.

With over 540 members, including undergraduates, graduate students, postdocs, staff, and faculty, Dr. Ginnan works with a thriving community of researchers. The center boasts 125 faculty members from 42 different departments, showcasing its broad expertise. Additionally, Dr. Ganan spearheads educational initiatives, such as the world's first Microbiome Sciences dual-title PhD program.

Dr. Nichole Ginnan emphasizes that microbiomes encompass more than just bacterial pathogens, including bacteria, fungi, and viruses. Understanding the intricate interactions within microbiomes is crucial, especially in the context of antimicrobial use. Dr. Nichole Ginnan advocates for interdisciplinary collaborations between microbiome and AMR researchers to address the complexities of AMR effectively.

To facilitate such collaborations, Dr. Nichole Ginnan encourages repurposing existing data and leveraging interdisciplinary expertise. For instance, clinicians can consider microbiome health when prescribing antibiotics, while microbiome researchers can analyze metagenomic data to explore AMR genes. Dr,.Nichole Ginnan highlighted the upcoming One Health Microbiome Symposium in May as a platform for fostering collaboration and mutual growth.

In conclusion, Dr, Ginnan believes that embracing a One Health approach and promoting interdisciplinary collaborations are essential steps in tackling antimicrobial resistance. The One Health Microbiome Center is poised to make significant contributions to global health initiatives.

Learn more by watching the full presentation as featured in the March Member Spotlight. 

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